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1

A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

Radwan, Amr, El-Lakkany, Naglaa M., William, Samia, El-Feky, Gina S., Al-Shorbagy, Muhammad Y., Saleh, Samira, Botros, Sanaa

Journal:

Parasites & Vectors

Year:

2019

Language:

english

File:

PDF, 1.03 MB

english, 2019

2

A model for southern mediterranean research institute self-assessment: A SWOT analysis-based approach to promote capacity building at Theodor Bilharz Research Institute in Cairo (Egypt)

Ghinolfi, Davide, El Baz, Hanan G., Borgonovi, Elio, Radwan, Amr, Laurence, Ola, Sayed, Hanan A., De Simone, Paolo, Abdelwadoud, Moaz, Stefani, Alessandro, Botros, Sanaa S., Filipponi, Franco

Journal:

Arab Journal of Gastroenterology

Year:

2014

Language:

english

File:

PDF, 305 KB

english, 2014

3

A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

Radwan, Amr, El-Lakkany, Naglaa M., William, Samia, El-Feky, Gina S., Al-Shorbagy, Muhammad Y., Saleh, Samira, Botros, Sanaa

Journal:

Parasites & Vectors

Year:

2019

File:

PDF, 1.03 MB

2019

4

Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus

El-Lakkany, Naglaa M., Hendawy, Ahmed S., Seif el-Din, Sayed H., Ashour, Ahmed A., Atta, Raafat, Abdel-Aziz, Abdel-Aziz H., Mansour, Ahmed M., Botros, Sanaa S.

Journal:

European Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 654 KB

english, 2016

5

Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways

Ahmed, Lamiaa A., Salem, Maha B., Seif el-Din, Sayed H., El-Lakkany, Naglaa M., Ahmed, Hend O., Nasr, Sami M., Hammam, Olfat A., Botros, Sanaa S., Saleh, Samira

Journal:

European Journal of Pharmacology

Year:

2020

File:

PDF, 3.50 MB

2020

6

Effect of adamantylamide dipeptide as adjuvant therapy to praziquantel in mice infected with different S. mansoni isolates

SANAA BOTROS, MADIHA MAHMOUD, OLFAT HAMMAM, FATEN SALAH, ZDENEK ZIDEK, KAREL MASEK

Journal:

Year:

2006

Language:

english

File:

PDF, 720 KB

english, 2006

7

The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo

Botros, Sanaa S., El-Lakkany, Naglaa M., Seif el-Din, Sayed H., William, Samia, Sabra, Abdel-Nasser, Hammam, Olfat A., de Koning, Harry P.

Journal:

Experimental Parasitology

Year:

2019

Language:

english

File:

PDF, 1.85 MB

english, 2019

8

Praziquantel resistance

Botros, Sanaa S, Bennett, James L

Journal:

Expert Opinion on Drug Discovery

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

9

Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces

Ezzat, Shahira M., Salama, Maha M., Seif el-Din, Sayed H., Saleh, Samira, El-Lakkany, Naglaa M., Hammam, Olfat A., Salem, Maha B., Botros, Sanaa S.

Journal:

Pharmaceutical Biology

Year:

2016

Language:

english

File:

PDF, 1.84 MB

english, 2016

10

DRUG-METABOLIZING ENZYMES AND PRAZIQUANTEL BIOAVAILABILITY IN MICE HARBORING SCHISTOSOMA MANSONI ISOLATES OF DIFFERENT DRUG SUSCEPTIBILITIES

Botros, Sanaa S., Seif el-Din, Sayed H., El-Lakkany, Naglaa M., Sabra, Abdel Nasser A., Ebeid, Fatma A.

Journal:

Journal of Parasitology

Year:

2006

Language:

english

File:

PDF, 95 KB

english, 2006

11

Efficacy and Safety of Artemether in the Treatment of Chronic Fascioliasis in Egypt: Exploratory Phase-2 Trials

Keiser, Jennifer, Sayed, Hanan, El-Ghanam, Maged, Sabry, Hoda, Anani, Saad, El-Wakeel, Aly, Hatz, Christoph, Utzinger, Jürg, el-Din, Sayed Seif, El-Maadawy, Walaa, Botros, Sanaa, Diemert, David Joseph

Journal:

PLoS Neglected Tropical Diseases

Year:

2011

Language:

english

File:

PDF, 239 KB

english, 2011

12

Current status of sensitivity to praziquantel in a focus of potential drug resistance in Egypt

Sanaa Botros, Hanan Sayed, Neimat Amer, Maged El-Ghannam, James L. Bennett, Tim A. Day

Journal:

International Journal for Parasitology

Year:

2005

Language:

english

File:

PDF, 92 KB

english, 2005

13

Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment

Sanaa S. Botros, Olfat Hammam, Madiha Mahmoud, Robert Bergquist

Journal:

Year:

2010

Language:

english

File:

PDF, 639 KB

english, 2010

14

Comparative efficacy and bioavailability of different praziquantel brands

Sanaa Botros, Naglaa El-Lakkany, Sayed H. Seif el-Din, Abdel-Nasser Sabra, Magda Ibrahim

Journal:

Experimental Parasitology

Year:

2011

Language:

english

File:

PDF, 252 KB

english, 2011

15

Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

Botros, Sanaa S., William, Samia, Sabra, Abdel-Nasser A., El-Lakkany, Naglaa M., Seif el-Din, Sayed H., García-Rubia, Alfonso, Sebastián-Pérez, Victor, Blaazer, Antoni R., de Heuvel, Erik, Sijm, Maart

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2019

File:

PDF, 1.08 MB

2019

16

Antipyrine clearance in comparison to conventional liver function tests in hepatitis C virus patients

Madiha Mahmoud, Rania Abdel-Kader, Moataz Hassanein, Samira Saleh, Sanaa Botros

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 274 KB

english, 2007

17

Determination of ED50 values for praziquantel in praziquantel-resistant and -susceptible Schistosoma mansoni isolates

Donato Cioli, Sanaa S Botros, Katherine Wheatcroft-Francklow, Amadou Mbaye, Vaughan Southgate, Louis-Albert Tchuem Tchuenté, Livia Pica-Mattoccia, Anna Rita Troiani, Sayed H Seif el-Din, Abdel-Nasser

Journal:

International Journal for Parasitology

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

18

The immunological aspects of praziquantel in unsensitized mice with experimentally induced schistosome pulmonary granuloma

Sanaa S. Botros, Aisha A. Metwally, M.T. Khayyal

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

1984

Language:

english

File:

PDF, 1.79 MB

english, 1984

19

Potential effect of the medicinal plants Calotropis procera. Ficus elastica and Zingiber officinale against Schistosoma mansoni in mice

Seif el-Din, Sayed H., El-Lakkany, Naglaa M., Mohamed, Mona A., Hamed, Manal M., Sterner, Olov, Botros, Sanaa S.

Journal:

Pharmaceutical Biology

Year:

2014

Language:

english

File:

PDF, 263 KB

english, 2014

20

Response of Schistosoma mansoni Isolates Having Different Drug Sensitivity to Praziquantel Over Several Life Cycle Passages with and Without Therapeutic Pressure

Sabra, Abdel Nasser A., Botros, Sanaa S.

Journal:

Journal of Parasitology

Year:

2008

Language:

english

File:

PDF, 77 KB

english, 2008

21

Response of Schistosoma mansoni Isolates Having Different Drug Sensitivity to Praziquantel over Several Life Cycle Passages with and without Therapeutic Pressure

Abdel Nasser A. Sabra and Sanaa S. Botros

Journal:

Journal of Parasitology

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

22

Immunoregulatory potential of exogenous Schistosoma mansoni soluble egg antigen in a model of experimental schistosomiasis — I. Regulation of granuloma formation in vivo

Sanaa S. Botros, Hanaa I. Hassanein, Soad I. Hassan, Maha M. Akl, Saber S. Sakr, Zeinab A. Shaker, Gehan L. Hafez, Nemat M. El Ghorab, David A. Dean

Journal:

International Journal of Immunopharmacology

Year:

1995

Language:

english

File:

PDF, 864 KB

english, 1995

23

Induction of hepatic egg granuloma hyporesponsiveness in murine schistosomiasis mansoni by intravenous injection of small doses of soluble egg antigen

HANAA HASSANEIN, MAHA AKL, ZEINAB SHAKER, HANAN EL-BAZ, RAGIA SHARMY, IBRAHIM RABIAE, SANAA BOTROS

Journal:

Year:

1997

Language:

english

File:

PDF, 1.74 MB

english, 1997

24

Relationship between schistosomicidal drug efficacy, gonadal steroid hormonal changes and state of disease immunopathology in murine Schistosomiasis mansoni

Sanaa S. Botros, Salwa H. Salama, Maher Y. Estafan, Nawal E. Gomaa, Aisha A. Metwally, Fatma A. Ebeid

Journal:

Pharmacological Research

Year:

1990

Language:

english

File:

PDF, 719 KB

english, 1990

25

Subcutaneous implantation of the spleen as a new technique for experimental induction of hepatic Schistosoma mansoni egg granulomas

SanaàS. Botros, Nawal El-badrawi, E.H. El-raziky

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

1986

Language:

english

File:

PDF, 178 KB

english, 1986

26

Comparative effect of tiaprofenic acid and piroxicam alone and as adjuvants to antibiharzial therapy on pulmonary granuloma in unsensitized mice

Sanaa S. Botros, Aisha A. Metwally, Mohamed T. Khayyal

Journal:

International Journal of Immunopharmacology

Year:

1988

Language:

english

File:

PDF, 494 KB

english, 1988

27

Effect of combined praziquantel and recombinant glutathione S-transferase on resistance to reinfection in murine Schistosomiasis mansoni

Sanaa S. Botros, Ekram A. Makary, Kesmat M. Ahmed, Abdalla M. Ibrahim, Nawal N. Nashed, Hussein M.S. El-Nahal, Barbara L. Doughty, Hanaa I. Hassanein

Journal:

International Journal of Immunopharmacology

Year:

2000

Language:

english

File:

PDF, 101 KB

english, 2000

28

Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study

El-Lakkany, Naglaa M., El-Maadawy, Walaa H., Seif el-Din, Sayed H., Saleh, Samira, Safar, Marwa M., Ezzat, Shahira M., Mohamed, Salwa H., Botros, Sanaa S., Demerdash, Zeinab, Hammam, Olfat A.

Journal:

Journal of Traditional and Complementary Medicine

Year:

2018

Language:

english

File:

PDF, 2.01 MB

english, 2018

29

Altered immunoglobulin isotype profile and anti-immature worm surface immunoglobulins in mice harboring a praziquantel-resistant Schistosoma mansoni isolate

SOAD HANALLAH, NAGLAA EL-LAKKANY, SOHEIR MAHMOUD, MONA MOUSA, SANAA BOTROS

Journal:

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

30

Praziquantel in a Clay Nanoformulation Shows More Bioavailability and Higher Efficacy against Murine Schistosoma mansoni Infection

El-Feky, Gina S., Mohamed, Wael S., Nasr, Hanaa E., El-Lakkany, Naglaa M., Seif el-Din, Sayed H., Botros, Sanaa S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 657 KB

english, 2015

31

Immunohistopathological and biochemical changes in Schistosoma mansoni-infected mice treated with artemether

Sanaa S. Botros, Madiha R. Mahmoud, Mona M. Moussa, Mona M. Nosseir

Journal:

Journal of Infection

Year:

2007

Language:

english

File:

PDF, 964 KB

english, 2007

32

Impact of drug dosage and brand on bioavailability and efficacy of praziquantel

Aiesha Metwally, James Bennett, Sanaa Botros, Fatma Ebeid, Gamal-El Din M. El Attar

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 782 KB

english, 1995

33

Drug-Metabolizing Enzymes and Praziquantel Bioavailability in Mice Harboring Schistosoma mansoni Isolates of Different Drug Susceptibilities

Sanaa S. Botros, Sayed H. Seif el-Din, Naglaa M. El-Lakkany, Abdel Nasser A. Sabra and Fatma A. Ebeid

Journal:

Journal of Parasitology

Year:

2006

Language:

english

File:

PDF, 1.42 MB

english, 2006

34

Effect of specific chemotherapy on the immune response and resistance to reinfection in experimental schistosomiasis mansoni

Soad I. Hassan, Sanaa A. Botros, Hussein M. El-Nahal, Magda E. Azab, Zeinab A. Shaker, Ahmed A. El-Garem

Journal:

International Journal of Immunopharmacology

Year:

1990

Language:

english

File:

PDF, 655 KB

english, 1990

35

Effect of praziquantel on the immature stages of Schistosoma haematobium

Sanaa Botros, Livia Pica-Mattoccia, Samia William, Naglaa El-Lakkani, Donato Cioli

Journal:

International Journal for Parasitology

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

36

MCR Synthesis of Praziquantel Derivatives

Haixia Liu, Samia William, Eberhardt Herdtweck, Sanaa Botros, Alexander Dömling

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 3.04 MB

english, 2012

37

Validation of sensitivity to praziquantel using Schistosoma mansoni worm muscle tension and Ca2+-uptake as possible in vitro correlates to in vivo ED50 determination

Samia William, Sanaa Botros

Journal:

International Journal for Parasitology

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

38

Neutrophil CD64 as a Diagnostic Marker of Sepsis in Neonates

Elawady, Sanaa, Botros, Shahira K., Sorour, Ashraf E., Ghany, Eman Abdel, Elbatran, Gamal, Ali, Raghdaa

Journal:

Journal of Investigative Medicine

Year:

2014

Language:

english

File:

PDF, 433 KB

english, 2014

39

Chemical Profiling of Polyphenolics in Eucalyptus globulus and Evaluation of Its Hepato–Renal Protective Potential Against Cyclophosphamide Induced Toxicity in Mice

Ghareeb, Mosad A., Sobeh, Mansour, El-Maadawy, Walaa H., Mohammed, Hala Sh., Khalil, Heba, Botros, Sanaa, Wink, Michael

Journal:

Year:

2019

Language:

english

File:

PDF, 4.91 MB

english, 2019

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